Nanolayered siRNA delivery platforms for local silencing of CTGF reduce cutaneous scar contraction in third-degree burns
نویسندگان
چکیده
منابع مشابه
Third-degree chemical burns from chlorhexidine local antisepsis.
[a] HemaClear ® , a self-contained, sterile, exsanguinating tourniquet face. Chemical burn was also reported in a 4 year old boy who underwent general anesthesia for elective orchidopexy; within a few hours, the child developed erythema and blistering around the upper buttocks and natal cleft region. The author recommended saline rinsing after antisepsis [4]. In 1995, contact dermatitis involvi...
متن کاملComparison of Albizia Julibressin and Silver Sulfadiazine in Healing of Second and Third Degree Burns
BACKGROUND Large numbers of population suffer from burn annually. The promising treatment of burn has not been identified yet. Albizia julibressin (A. julibressin) in Fabaceae family is popular for its antiseptic activity. This prospective study was designed to compare the wound healing effects of A. julibressin gel (AG) with silver sulfadiazine (SSD). METHODS This single blind clinical tria...
متن کاملQuantitative changes of mast cells following topical application of honey on third degree burns in rats
The purpose of present study was determination of number changes of mast cells in a honey treated experimental model of third degree burn. A third degree burn was made in 24 adult female rats by direct contact of skin with boiling water for 8 seconds. Rats were divided randomly into four groups. Group 1: Burns of this group remained untreated (control group). Groups 2 and 3: Burns of these grou...
متن کاملQuantitative changes of mast cells following topical application of honey on third degree burns in rats
The purpose of present study was determination of number changes of mast cells in a honey treated experimental model of third degree burn. A third degree burn was made in 24 adult female rats by direct contact of skin with boiling water for 8 seconds. Rats were divided randomly into four groups. Group 1: Burns of this group remained untreated (control group). Groups 2 and 3: Burns of these grou...
متن کاملNanolayered siRNA dressing for sustained localized knockdown.
The success of RNA interference (RNAi) in medicine relies on the development of technology capable of successfully delivering it to tissues of interest. Significant research has focused on the difficult task of systemic delivery of RNAi; however its local delivery could be a more easily realized approach. Localized delivery is of particular interest for many medical applications, including the ...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2016
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2016.04.007